Description: Silver sulfadiazine is a sulfonamide with broad antimicrobial activity that acts upon the bacterial cell wall and cell membrane of Gram-positive and Gram-negative organisms and even yeasts.
Absorption: Up to approx 10% of sulfadiazine and some silver may be absorbed; depending on the nature of the wound and treatment regimen.
Excretion: Silver: Slowly excreted via the faeces; Sulfadiazine: Via urine (6.6% within 5 days).